Dipakranjan Mal

Professor of Chemistry

IIT Kharagpur 721302



Born: 03-04-52; Family: Sobhana, Rudrajit, Indrajit





► PhD, 1981, GPA (4/4), University of Missouri, Kansas City, USA; Mentor: Prof. L. L. McCoy

► MSc, 1974, 1st Class (71%), University College of Science, Calcutta University

► BSc (Hons), 1972, 1st Class (65%), Ramakrishna Mission Vidyamandira, Belur Math, Calcutta University

► HS, 1969, 1st Div (75%), Banamalichatta High School, Contai, West Bengal Board of Higher Secondary


Professional Affiliations:


► Professor (Higher administrative grade) (2014-present), Indian Institute of Technology, Kharagpur

► Professor (Higher administrative grade) and Head (2011-2014), Indian Institute of Technology, Kharagpur

► Professor (Higher administrative grade) (2010-2011), Indian Institute of Technology, Kharagpur

► Professor (2004 -2010), Indian Institute of Technology, Kharagpur

► Associate Professor (19962004), Indian Institute of Technology, Kharagpur

► Visiting Professor, 1998, State University of New York, Albany, USA

► Assistant Professor (19871996), Indian Institute of Technology, Kharagpur

► Lecturer (19841987), Bose Institute, Kolkata

► Research Associate (1981-1984), Oregon Graduate Center, USA; Mentor: Prof. F. M. Hauser

► Teaching Assistant (19761981), University of Missouri, Kansas City, USA

► Junior Research Fellow, CSIR, New Delhi, 1976, Calcutta University: Mentor: Prof. P. L. Majumder




► Gold Medal and L. Mitra proficiency prize of R K Mission Vidyamandira, Belur Math

► Junior Research Fellowship, CSIR, New Delhi

► Phi Kappa Phi Honor Certificate of the University of Missouri, Kansas City, USA


Editorial Board Membership: Organic Chemistry International


Fellow: i) West Bengal Academy of Science and Technology ii) Royal Society of Chemistry (UK)




► Life Member of the Indian Chemical Society, Kolkata

► Life Member of the Chemical Research Society of India, Bangalore

► Member of the American Chemical Society


Specialization: Synthetic Organic Chemistry & Natural Product Chemistry


Research Interests:


► Total synthesis of bioactive polyketides: angucyclines, anthracyclines and kinamycins

► Synthesis of phthalides, phenolics, quinonoids, isocoumarins and furocoumarins of medicinal interests

► Synthesis of carbazole natural products and indole derivatives

► Anionic and thermal domino reactions; Hauser annulation and epoxycyclopentenone rearrangement

► Chemistry of organosulfur, hypervalent iodine reagents, metal carbonyl complexes and small ring compounds


Research Summary:


► No. of Publications, book chapters and patents: 106

► No. of PhD students supervised & being supervised: 31

► No. of MSc students supervised & being supervised: 42

► No. of Sponsored Research Projects completed & on-going: 12


Representative Publications:


1. Phthalides and Phthalans: Synthetic Methodologies and their Applications in the Total Synthesis, Karmakar, R.; Pahari, P.; Mal, D. Chem. Rev. 2014, 114, 62136284.

2. Total synthesis of chlorocyclinone A, a PPAR-gamma antagonist, Karmakar, R.; Mal, D. J. Org. Chem. 2012, 77, 1023510248.


3. A rapid entry to C-prenylcarbazoles: total synthesis of clausamines C-D, clausevatine D, and clausine F, Jana, A.; Mal D. Chem. Commun., 2010, 46, 44114413.


4. Total synthesis of euplectin, a natural product with a chromone fused indenone, Mal, D.; De, S. R. Org. Lett. 2009, 11, 4398-4401.


5. DBU-CH3I, a potential substitute for CH2N2 for the preparation of methyl esters: studies with assorted carboxylic acids, D. Mal, A. Jana, S. Ray, S. Bhattacharya, A. Patra and S. De, Synth. Commun. 2008, 38, 3937-3946.


6. Recent advances in the Hauser annulation, Mal, D. and Pahari, P. Chem. Rev. 2007, 107, 1892-1918.


7. A brief and convergent synthetic route to defucogilvocarcin M chromophore: The formal synthesis of WS 5995 A & C, D. Mal, A. Patra, P. Pahari and S. Roy, J. Org. Chem. 2005, 70, 9017.


8. Total synthesis of coriandrin and 7-demethylcoriandrin via a new isocoumarin synthesis, D. Mal, M. Bandyopadhyay, S. K. Ghorai and K. Datta, Tetrahedron Lett. 2000, 41, 3677.


9. Tandem Cope-Cheletropic reaction: A new molecular rearrangement, D. Mal and N. K. Hazra, Chem. Commun. 1996, 1181.


10. The first approach to kinamycin antibiotics: synthesis of kinafluorenone scaffold, D. Mal and N. K. Hazra, Tetrahedron Lett. 1996, 37, 2641.


11. Thiophthalides: A novel class of arene-annulating agents: synthesis of polynuclear hydroaromatic compounds, D. Mal, R. Pal and K. V. S. N. Murty, J. Chem. Soc. Chem. Commun. 1992, 821.


12. Regio- and Stereo-specific construction of anthracyclinones: total synthesis of ()-γ-citromycinone and ()-dimethyl 6-deoxydaunomycinone and ()-dimethyl 6-deoxyadriamycinone, F. M. Hauser, P. Hewawasam and D. Mal, J. Am. Chem. Soc. 1988, 110, 2919.


13. Intramolecular hydrogen bonding and acidity of some γ-hydroxy and γ-methoxy-α,-unsaturated carboxylic acids, L. L. McCoy and D. Mal, J. Org. Chem. 1984, 49, 939.


14. Three-membered Rings: Reaction of 1-halocyclopropane 1,2-diesters with 1,8-diazabicyclo[5.4.0]undec-7-ene, unexpected Products, L. L. McCoy and D. Mal, J. Org. Chem. 1981, 46, 1016.


15. Structure of moronic acid, P. L. Majumder, R. N. Maity, S. K. Panda, D. Mal, M.S. Raju and E. Wenkert, J. Org. Chem. 1979, 44, 2811.